Adrafinil improved concentration and alertness.

Eugeroic stands for “good arousal”. The unique ability of eugeroic lies in its power to only stimulate when stimulation is needed. Consequently the “highs and lows” linked with other stimulants like amphetamine are not present with eugeroics. Adrafinil is a part of the new class of eugeroic drug.

Human studies have revealed how Adrafinil has clinical effectiveness in the elderly by promoting vigilance and enhancing the mood.

Adrafinil has been approved in many countries for treating narcolepsy, Adrafinil offers improved concentration and alertness. It also increases energy levels memory and vigilance. It lowers fatigue and sharpens mental focus. It prevents side effects such as agitation, anxiety and interrupted sleep patterns all of which are regularly linked with conventional stimulants.

 
Among animal studies the most outstanding behavioural response to Adrafinil is increased activity. This was first made aware by Dutell et al who were able to report a dose dependent rise in activity at doses of 64 and 124 mg/kg among mice.
Milhaud and Klein researched the effects of Adrafinil and nocturnal activity among monkeys and discovered how a 60 mg/kg dose nearly doubled activity.

 
These behavior stimulating effects of Adrafinil vary from other psychostimulants in two vital ways. Firstly in contrast to amphetamine, it does not normally generate stereotypical behavior except perhaps during very high doses. Secondly Adrafinil effects are not anxiogenic.

 
Kohler and Lubin conducted an open trial that studied the effects of Adrafinil among 304 patients who demonstrated problems in attention, concentration, showing depression and affective troubles. These patients were given Adrafinil over a period of 3 months. Evaluations were made on attention, concentration, vigilance and perceptual-motor skills. Difficulties of daily life were also assessed along with depression and anxiety scales. They discovered considerable improvements for every measure. This study particularly revealed improved concentration and alertness along with vigilance.