Wednesday, 31 August 2011

Adrafinil : Effective anti depressant drug

Adrafinil also known as Olmifon is a eugeroic drug specifically designed to increase mental alertness and improve brain function in both healthy individuals and people with mind related disorders such as narcolepsy, dementia, and depression.

Eugeroic is a Greek term meaning ‘good arousal’ used for substances which have an effect of waking up the brain. Adrafinil by acting upon the central nervous system is known to stimulate the noradrenergic post-synaptic receptors, increase glutamatergic transmission, and increase or ignite the action of orexinergic neurons that increase mental alertness.

Adrafinil thus by stimulating the central nervous system and improving chemical reactions in the brain boosts concentration, increase energy, increase mental alertness and improves memory.

Since Adrafinil boosts mood, improves focus, increase energy, heightens motivation and tackles sleep disorders it has been proved to be extremely useful as a anti depressant drug as it addresses most of the symptoms of clinical depression.

Depression is a mental disorder which more often than not is a result of impaired chemical reactions in the brain than a psychological illness. The underlying cause of clinical depression can be some psychological problem, but it has been observed that people with depressive disorders all suffer from some abnormal chemical reactions taking place in their brain chemistry.

Also depression is a common mental disorder found in many elderly people. This shows that as we age along with a decline in our physical capacities our brain function too declines leading to depression and sometimes serious disorders such as senile dementia, Alzhiemer’s disease and Parkinson’s disease

Adrafinil Olmifon with its stimulating effect upon the brain nerves and cells produces invigorating effect upon the mood, mental functioning, recall and sleep patterns.

With increased mental energy and motivation to perform your day to day activities with interest, the depressive symptoms of fatigue and lack of interest in daily chores would automatically vanish.

It has been observed that depressive people have problem getting proper sleep at night and in the day time they suffer from excessive fatigue and bouts of sleepiness to perform their tasks effectively. Adrafinily by increasing mental alertness addresses this problem from the root and help in regularising the sleep patterns by keeping one alert and awake during the daytime to perform one’s work efficiently.

Though this anti depressant drug is available from over the counter, you must take Adrafinil Olmifon under the supervision of a certified medical professional to rule out any complications or adverse effects. Adrafinil has no known toxicity or adverse effects if taken in recommended doses under the guidance of a doctor.

Wednesday, 27 July 2011

Adrafinil improved concentration and alertness.


Eugeroic stands for “good arousal”. The unique ability of eugeroic lies in its power to only stimulate when stimulation is needed. Consequently the “highs and lows” linked with other stimulants like amphetamine are not present with eugeroics. Adrafinil is a part of the new class of eugeroic drug.

Human studies have revealed how Adrafinil has clinical effectiveness in the elderly by promoting vigilance and enhancing the mood.

Adrafinil has been approved in many countries for treating narcolepsy, Adrafinil offers improved concentration and alertness. It also increases energy levels memory and vigilance. It lowers fatigue and sharpens mental focus. It prevents side effects such as agitation, anxiety and interrupted sleep patterns all of which are regularly linked with conventional stimulants.
 
Among animal studies the most outstanding behavioural response to Adrafinil is increased activity. This was first made aware by Dutell et al who were able to report a dose dependent rise in activity at doses of 64 and 124 mg/kg among mice.
Milhaud and Klein researched the effects of Adrafinil and nocturnal activity among monkeys and discovered how a 60 mg/kg dose nearly doubled activity.
 
These behavior stimulating effects of Adrafinil vary from other psychostimulants in two vital ways. Firstly in contrast to amphetamine, it does not normally generate stereotypical behavior except perhaps during very high doses. Secondly Adrafinil effects are not anxiogenic.
 
Kohler and Lubin conducted an open trial that studied the effects of Adrafinil among 304 patients who demonstrated problems in attention, concentration, showing depression and affective troubles. These patients were given Adrafinil over a period of 3 months. Evaluations were made on attention, concentration, vigilance and perceptual-motor skills. Difficulties of daily life were also assessed along with depression and anxiety scales. They discovered considerable improvements for every measure. This study particularly revealed improved concentration and alertness along with vigilance.